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BARDA Preclinical Testing Services for Botulinum Neurotoxin Therapeutics

One of the challenges faced by many early academic and small business research partners is the cost associated with demonstrating a therapeutic candidate’s effectiveness in relevant efficacy models. BARDA invites researchers to submit proposals to the Botulinum Neurotoxin (BoNT) Candidate

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BARDA Awards $117 Million for First Clinical Trial for New ARDS Treatments

The Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response (ASPR), announced a $117 million contract to simultaneously evaluate three novel therapeutics to treat hospitalized adult patients with acute respiratory

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Pushing back against viruses with pandemic potential

.Health Security Systems Australia (HSSA) is working with experts at the University of Melbourne at the Peter Doherty Institute for Infection and Immunity (Doherty Institute), The University of Queensland’s National Biologics Facility, and industry partner Biointelect Pty Ltd to develop a novel

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Chimerix Announces Sale of TEMBEXA to Emergent BioSolutions

Chimerix, a biopharmaceutical company whose mission it is to develop medicines that meaningfully improve and extend the lives of patients facing deadly diseases, today announces it has entered into a definitive agreement with Emergent BioSolutions Inc. (Emergent) to acquire its exclusive

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SIGA Receives FDA approval for IV Formulation of TPOXX

SIGA Technologies, Inc. (SIGA), a commercial-stage pharmaceutical company focused on the health security market, today announced that the U.S. Food and Drug Administration (FDA) approved the intravenous (IV) formulation of TPOXX for the treatment of smallpox. The IV formulation is an important

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DOD Awards Dynavax $22 Million for Plague Vaccine Clinical Trial

The U.S. Department of Defense (DOD) awarded Dynavax Technologies Corporation with an agreement worth approximately $22 million over two and a half years, to execute a clinical trial combining the DOD’s recombinant plague (rF1V) vaccine with its own CpG 1018® adjuvant. Under the agreement,

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FDA approves first treatment for Ebola

On October 14 the U.S. Food and Drug Administration approved Inmazeb (atoltivimab, maftivimab, and odesivimab-ebgn), a mixture of three monoclonal antibodies, as the first FDA-approved treatment for Zaire ebolavirus (Ebola virus) infection in adult and pediatric

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CEPI grants $9M to Inovio to develop coronavirus vaccine

Inovio Pharmaceuticals, USA has announced the Coalition for Epidemic Preparedness Innovations (CEPI) has awarded Inovio a grant of up to $9 million to develop a vaccine against the recently emerged strain of coronavirus (2019-nCoV). This initial CEPI funding will support Inovio's

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Cyanide Autoinjector Development

The University of Minnesota Twin Cities and Windgap Medical have received a $3.2 million grant from the National Institutes of Health (NIH) to develop a new device to quickly administer a recently developed antidote for cyanide poisoning.

Under the grant, researchers from the

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BARDA Procures NexoBrid for Emergency Response

MediWound Ltd. and its U.S. commercial partner Vericel Corporation have announced that BARDA has begun procuring NexoBrid for emergency stockpile as part of the HHS mission to build national preparedness for public

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