---
title: "Crossject’s ZENEO Auto-Injector's usability further demonstrated in extreme HAZMAT conditions"
description: "CBRNe World provides those tasked with defending against CBRN and IED threats with the essential practical, scientific and political information. Access the current and previous issues of the magazine by registering as a member."
url: "https://cbrneworld.com/news/subscribers/crossjects-zeneo-auto-injectors-usability-further-demonstrated-in-extreme-hazmat-conditions"
date: "2026-07-30T21:15:31+00:00"
language: "en-GB"
---

#  Crossject’s ZENEO Auto-Injector's usability further demonstrated in extreme HAZMAT conditions

 Written by Zoe Rutherford on 18 November 2024.

Crossject, a specialty pharma company developing the award-winning needle-free ZENEO® auto-injector to deliver life-saving medicines in emergency situations, has successfully completed a human factors study under extreme stress conditions. The test, designed to simulate a chemical attack zone or a field hospital setting, included disorienting factors such as sirens and flashlights in the dark. Study participants were equipped with HAZMAT protection, including full-body CBRN (Chemical, Biological, Radiological, Nuclear) suits and gloves covered in soap, simulating the worst-case scenario for first responders.

All 75 untrained participants successfully activated the ZENEO® Midazolam on five adult or child mannequins simulating victims of a neurotoxin attack. The study results confirmed the usability of ZEPIZURE® rescue therapy, strongly indicating that the ZENEO® auto-injector is suitable for rapid, mass administration by untrained caregivers in extreme emergency conditions.

This study has been supported with federal funds from the U.S. Department of Health and Human Services; Administration for Strategic Preparedness and Response; Biomedical Advanced Research and Development Authority (BARDA), under contract number 75A50122C00031.

“We are very pleased with the outcome of this HAZMAT study, which underscores again the exceptional usability of Crossject’s ZENEO® auto-injector - even when administered en masse by untrained personnel under extreme conditions,” said Patrick Alexandre, CEO of Crossject.

In an earlier human factors study performed in 2022, Crossject demonstrated high usability with the ZENEO® needle-free auto-injector among 60 untrained users across four different profiles in a simulated epileptic crisis.

 [Medical Countermeasure](https://cbrneworld.com/component/tags/tag/medical-countermeasure)

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